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Molecular dynamics of the full-length p53 monomer
The p53 protein is frequently mutated in a very large proportion of human tumors, where it seems to acquire gain-of-function activity that facilitates tumor onset and progression. A possible mechanism is the ability of mutant p53 proteins to physically interact with other proteins, including members...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875683/ https://ncbi.nlm.nih.gov/pubmed/23974096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26162 |
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