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Structural Evolution and Dynamics of the p53 Proteins

The family of the p53 tumor suppressive transcription factors includes p73 and p63 in addition to p53 itself. Given the high degree of amino-acid-sequence homology and structural organization shared by the p53 family members, they display some common features (i.e., induction of cell death, cell-cyc...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Chillemi, Giovanni, Kehrloesser, Sebastian, Bernassola, Francesca, Desideri, Alessandro, Dötsch, Volker, Levine, Arnold J., Melino, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378015/
https://ncbi.nlm.nih.gov/pubmed/27091942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028308
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