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Structural evolution of C-terminal domains in the p53 family

The tetrameric state of p53, p63, and p73 has been considered one of the hallmarks of this protein family. While the DNA binding domain (DBD) is highly conserved among vertebrates and invertebrates, sequences C-terminal to the DBD are highly divergent. In particular, the oligomerization domain (OD)...

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Bibliographic Details
Main Authors: Ou, Horng Der, Löhr, Frank, Vogel, Vitali, Mäntele, Werner, Dötsch, Volker
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933395/
https://ncbi.nlm.nih.gov/pubmed/17581633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601764
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