Mutual Antagonism between the Ebola Virus VP35 Protein and the RIG-I Activator PACT Determines Infection Outcome

The cytoplasmic pattern recognition receptor RIG-I is activated by viral RNA and induces type I IFN responses to control viral replication. The cellular dsRNA binding protein PACT can also activate RIG-I. To counteract innate antiviral responses, some viruses, including Ebola virus (EBOV), encode pr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Luthra, Priya, Ramanan, Parameshwaran, Mire, Chad E., Weisend, Carla, Tsuda, Yoshimi, Yen, Benjamin, Liu, Gai, Leung, Daisy W., Geisbert, Thomas W., Ebihara, Hideki, Amarasinghe, Gaya K., Basler, Christopher F.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875338/
https://ncbi.nlm.nih.gov/pubmed/23870315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.06.010
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares