CYP2E1-Dependent and Leptin-Mediated Hepatic CD57 Expression on CD8+ve T Cells aid Progression of Environment-Linked Nonalcoholic Steatohepatitis

Environmental toxins induce a novel CYP2E1/leptin signaling axis in liver. This in turn activates a poorly characterized innate immune response that contributes to nonalcoholic steatohepatitis (NASH) progression. To identify the relevant subsets of T-lymphocytes in CYP2E1-dependent, environment-link...

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Autori principali: Seth, Ratanesh Kumar, Das, Suvarthi, Kumar, Ashutosh, Chanda, Anindya, Kadiiska, Maria B., Michelotti, Gregory, Manautou, Jose, Diehl, Anna Mae, Chatterjee, Saurabh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874401/
https://ncbi.nlm.nih.gov/pubmed/24211274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.10.029
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