Cyclin D1b in Human Breast Carcinoma and Coexpression with Cyclin D1a Is Associated with Poor Outcome

BACKGROUND/AIM: Cyclin D1 is a mediator of cell-cycle control that is frequently overexpressed in primary ductal breast carcinomas, but its role is controversial. A polymorphism in the CCND1 gene, G870A, results in an aberrantly spliced protein (cyclin D1b) lacking the Thr-286 phosphorylation site n...

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Asıl Yazarlar: ABRAMSON, VANDANA GUPTA, TROXEL, ANDREA B., FELDMAN, MICHAEL, MIES, CAROLYN, WANG, YAN, SHERMAN, LAUREN, MCNALLY, SARA, DIEHL, ALAN, DEMICHELE, ANGELA
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874215/
https://ncbi.nlm.nih.gov/pubmed/20530440
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