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Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity

Malaria parasites replicate asexually within their mammalian hosts as haploid cells and are subject to DNA damage from the immune response and chemotherapeutic agents that can significantly disrupt genomic integrity. Examination of the annotated genome of the parasite Plasmodium falciparum identifie...

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Detalhes bibliográficos
Main Authors: Kirkman, Laura A., Lawrence, Elizabeth A., Deitsch, Kirk W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874194/
https://ncbi.nlm.nih.gov/pubmed/24089143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt881
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