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Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells

How tumor suppressor p53 selectively responds to specific signals, especially in normal cells, is poorly understood. We performed genome-wide profiling of p53 chromatin interactions and target gene expression in human embryonic stem cells (hESCs) in response to early differentiation, induced by reti...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Akdemir, Kadir C., Jain, Abhinav K., Allton, Kendra, Aronow, Bruce, Xu, Xueping, Cooney, Austin J., Li, Wei, Barton, Michelle Craig
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874181/
https://ncbi.nlm.nih.gov/pubmed/24078252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt866
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