Foxa1 Functions as a Pioneer Transcription Factor at Transposable Elements to Activate Afp during Differentiation of Embryonic Stem Cells

Epigenetic control of genes that are silent in embryonic stem cells, but destined for expression during differentiation, includes distinctive hallmarks, such as simultaneous activating/repressing (bivalent) modifications of chromatin and DNA hypomethylation at enhancers of gene expression. Although...

Full description

Saved in:
Bibliographic Details
Main Authors: Taube, Joseph H., Allton, Kendra, Duncan, Stephen A., Shen, Lanlan, Barton, Michelle Craig
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871482/
https://ncbi.nlm.nih.gov/pubmed/20348100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088096
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items