Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells

Transposable elements (TEs) compose about 40% of the murine genome. Retrotransposition of active TEs such as LINE-1 (L1) tremendously impacts genetic diversification and genome stability. Therefore, transcription and transposition activities of retrotransposons are tightly controlled. Here, we show...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Dai, Qian, Shen, Yang, Wang, Yan, Wang, Xin, Francisco, Joel Celio, Luo, Zhuojuan, Lin, Chengqi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716208/
https://ncbi.nlm.nih.gov/pubmed/29036642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx841
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