A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron

Genomic imprinting is an epigenetic regulation that leads to gene expression in a parent-of-origin specific manner. AFF3, the central component of the Super Elongation Complex-like 3 (SEC-L3), is enriched at both the intergenic-differentially methylated region (IG-DMR) and the Meg3 enhancer within t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wang, Yan, Shen, Yang, Dai, Qian, Yang, Qian, Zhang, Yue, Wang, Xin, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388394/
https://ncbi.nlm.nih.gov/pubmed/28180295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1051
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