Meg3-DMR, not the Meg3 gene, regulates imprinting of the Dlk1-Dio3 locus

The imprinted delta like 1 homolog (DLK1) - thyroxine deiodinase type III (DIO3) locus regulates development and growth. Its imprinting regulation involves two differentially methylated regions (DMRs), intergenic-DMR (IG-DMR) and maternally expressed gene 3-DMR (Meg3-DMR). In mice, a maternal deleti...

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Udgivet i:Dev Biol
Main Authors: Zhu, Wende, Botticelli, Erin M., Kery, Rachel E., Mao, Yanfei, Wang, Xin, Yang, Anli, Wang, Xianling, Zhou, Jie, Zhang, Xun, Soberman, Roy J., Klibanski, Anne, Zhou, Yunli
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754764/
https://ncbi.nlm.nih.gov/pubmed/31301299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.07.005
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