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Silencing of the Imprinted DLK1-MEG3 Locus in Human Clinically Nonfunctioning Pituitary Adenomas

DLK1-MEG3 is an imprinted locus consisting of multiple maternally expressed noncoding RNA genes and paternally expressed protein-coding genes. The expression of maternally expressed gene 3 (MEG3) is selectively lost in clinically nonfunctioning adenomas (NFAs) of gonadotroph origin; however, express...

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Bibliographische Detailangaben
Hauptverfasser: Cheunsuchon, Pornsuk, Zhou, Yunli, Zhang, Xun, Lee, Hang, Chen, Wendy, Nakayama, Yuki, Rice, Kimberley A., Tessa Hedley-Whyte, E., Swearingen, Brooke, Klibanski, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181372/
https://ncbi.nlm.nih.gov/pubmed/21871428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.002
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