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Foxa1 Functions as a Pioneer Transcription Factor at Transposable Elements to Activate Afp during Differentiation of Embryonic Stem Cells

Epigenetic control of genes that are silent in embryonic stem cells, but destined for expression during differentiation, includes distinctive hallmarks, such as simultaneous activating/repressing (bivalent) modifications of chromatin and DNA hypomethylation at enhancers of gene expression. Although...

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Detalles Bibliográficos
Main Authors: Taube, Joseph H., Allton, Kendra, Duncan, Stephen A., Shen, Lanlan, Barton, Michelle Craig
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871482/
https://ncbi.nlm.nih.gov/pubmed/20348100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088096
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