LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56

Recent evidence suggests that lncRNAs play an integral regulatory role in numerous functions, including determination of cellular identity. We determined global expression (RNA-seq) and genome wide profiles (ChIP-seq) of histone post-translational modifications and p53 binding in human embryonic ste...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Jain, Abhinav K, Xi, Yuanxin, McCarthy, Ryan, Allton, Kendra, Akdemir, Kadir C, Patel, Lalit R, Aronow, Bruce, Lin, Chunru, Li, Wei, Yang, Liuqing, Barton, Michelle C
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137794/
https://ncbi.nlm.nih.gov/pubmed/27912097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.10.039
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