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Unraveling the therapeutic potential of the LncRNA-dependent noncanonical Hedgehog pathway in cancer

Acquired resistance to Hedgehog pathway inhibitors has been reported in the clinical setting and upregulation of noncanonical Hedgehog signaling is one of the major underlying mechanisms behind this resistance. As demonstrated in our recent study, greater clinical efficacy might be achieved by focus...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Oncol
Autori principali: Xing, Zhen, Lin, Chunru, Yang, Liuqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905365/
https://ncbi.nlm.nih.gov/pubmed/27308519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.998900
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