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Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers

Hematopoietic stem cell transplantation has been used for more than 50 years to combat hematologic malignancies. In addition to being the first stem cell therapy, transplantation has provided evidence for the potent anti-tumor effects of T cells. Facilitating T-cell-based immunity against malignanci...

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Détails bibliographiques
Auteurs principaux: Ghosh, Arnab, Holland, Amanda M., van den Brink, Marcel R.M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874121/
https://ncbi.nlm.nih.gov/pubmed/24329800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12142
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