Multiple knockout mouse models reveal lincRNAs are required for life and brain development

Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological conditions, we have developed a collection of 18 lncRN...

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Detaylı Bibliyografya
Asıl Yazarlar: Sauvageau, Martin, Goff, Loyal A, Lodato, Simona, Bonev, Boyan, Groff, Abigail F, Gerhardinger, Chiara, Sanchez-Gomez, Diana B, Hacisuleyman, Ezgi, Li, Eric, Spence, Matthew, Liapis, Stephen C, Mallard, William, Morse, Michael, Swerdel, Mavis R, D’Ecclessis, Michael F, Moore, Jennifer C, Lai, Venus, Gong, Guochun, Yancopoulos, George D, Frendewey, David, Kellis, Manolis, Hart, Ronald P, Valenzuela, David M, Arlotta, Paola, Rinn, John L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2013
Konular:
Developmental Biology and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874104/
https://ncbi.nlm.nih.gov/pubmed/24381249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01749
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