Targeting Human Telomeric G-Quadruplex DNA and Inhibition of Telomerase Activity With [(dmb)(2)Ru(obip)Ru(dmb)(2)](4+)

Inhibition of telomerase by inducing/stabilizing G-quadruplex formation is a promising strategy to design new anticancer drugs. We synthesized and characterized a new dinuclear complex [(dmb)(2)Ru(obip)Ru(dmb)(2)](4+) (dmb = 4,4’-dimethyl-2,2’-bipyridine, obip = (2-(2-pyridyl)imidazo[4,5-f][1,10]phe...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Shi, Shuo, Gao, Shane, Cao, Tongcheng, Liu, Jie, Gao, Xing, Hao, Jian, Lv, Chunyan, Huang, Hailiang, Xu, Jun, Yao, Tianming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874006/
https://ncbi.nlm.nih.gov/pubmed/24386376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084419
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items