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Functional Characterization of a Full Length Pregnane X Receptor, Expression in vivo, and Identification of PXR Alleles in Zebrafish (Danio rerio)

The pregnane X receptor (PXR) (nuclear receptor NR1I2) is a ligand activated transcription factor, mediating responses to diverse xenobiotic and endogenous chemicals. The properties of PXR in fish are not fully understood. Here we report on cloning and characterization of full-length PXR of zebrafis...

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書誌詳細
主要な著者: Bainy, Afonso C. D., Kubota, Akira, Goldstone, Jared V., Lille-Langøy, Roger, Karchner, Sibel I., Celander, Malin C., Hahn, Mark E., Goksøyr, Anders, Stegeman, John J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873750/
https://ncbi.nlm.nih.gov/pubmed/24121122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2013.09.014
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