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Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Ligands that bind to the allosteric-binding sites on muscarinic acetylcholine receptors alter the conformation of the classical-binding sites of these receptors and either diminish or increase their affinity for muscarinic agonists and classical antagonists. It is not known whether the resulting con...

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Bibliographic Details
Main Authors: Jakubík, J, Bacáková, L, Lisá, V, el-Fakahany, E E, Tucek, S
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC38737/
https://ncbi.nlm.nih.gov/pubmed/8710935
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