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Effectively Delivering a Unique Hsp90 Inhibitor Using Star Polymers

[Image: see text] We report the synthesis of a novel heat shock protein 90 (hsp90) inhibitor conjugated to a star polymer. Using reversible addition–fragmentation chain-transfer (RAFT) polymerization, we prepared star polymers comprising PEG attached to a predesigned functional core. The stars were...

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Detalhes bibliográficos
Main Authors: Kim, Seong Jong, Ramsey, Deborah M., Boyer, Cyrille, Davis, Thomas P., McAlpine, Shelli R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873631/
https://ncbi.nlm.nih.gov/pubmed/24379910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400082b
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