Differences in the Regulation of K-Ras and H-Ras Isoforms by Monoubiquitination

Ras GTPases are signaling switches that control critical cellular processes including gene expression, differentiation, and apoptosis. The major Ras isoforms (K, H, and N) contain a conserved core GTPase domain, but have distinct biological functions. Among the three Ras isoforms there are clear dif...

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Main Authors: Baker, Rachael, Wilkerson, Emily M., Sumita, Kazutaka, Isom, Daniel G., Sasaki, Atsuo T., Dohlman, Henrik G., Campbell, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873545/
https://ncbi.nlm.nih.gov/pubmed/24247240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.525691
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