RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies

Chromosome 3p21.3 region is frequently (>90%) deleted in lung and other major human carcinomas. We subdivided 3p21.3 into LUCA and AP20 subregions and discovered frequent homozygous deletions (10-18%) in both subregions. This finding strongly implies that they harbor multiple tumor suppressor gen...

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Detalhes bibliográficos
Main Authors: Kashuba, Vladimir I., Li, Jingfeng, Wang, Fuli, Senchenko, Vera N., Protopopov, Alexey, Malyukova, Alena, Kutsenko, Alexey S., Kadyrova, Elena, Zabarovska, Veronika I., Muravenko, Olga V., Zelenin, Alexander V., Kisselev, Lev L., Kuzmin, Igor, Minna, John D., Winberg, Gösta, Ernberg, Ingemar, Braga, Eleonora, Lerman, Michael I., Klein, George, Zabarovsky, Eugene R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387347/
https://ncbi.nlm.nih.gov/pubmed/15051889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401238101
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