NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes
Methylation, deletions, and amplifications of cancer genes constitute important mechanisms in carcinogenesis. For genome-wide analysis of these changes, we propose the use of NotI clone microarrays and genomic subtraction, because NotI recognition sites are closely associated with CpG islands and ge...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149436/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132271699 |
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