RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies

Chromosome 3p21.3 region is frequently (>90%) deleted in lung and other major human carcinomas. We subdivided 3p21.3 into LUCA and AP20 subregions and discovered frequent homozygous deletions (10-18%) in both subregions. This finding strongly implies that they harbor multiple tumor suppressor gen...

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Bibliographic Details
Main Authors: Kashuba, Vladimir I., Li, Jingfeng, Wang, Fuli, Senchenko, Vera N., Protopopov, Alexey, Malyukova, Alena, Kutsenko, Alexey S., Kadyrova, Elena, Zabarovska, Veronika I., Muravenko, Olga V., Zelenin, Alexander V., Kisselev, Lev L., Kuzmin, Igor, Minna, John D., Winberg, Gösta, Ernberg, Ingemar, Braga, Eleonora, Lerman, Michael I., Klein, George, Zabarovsky, Eugene R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387347/
https://ncbi.nlm.nih.gov/pubmed/15051889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401238101
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