High Mutability of the Tumor Suppressor Genes RASSF1 and RBSP3 (CTDSPL) in Cancer

BACKGROUND: Many different genetic alterations are observed in cancer cells. Individual cancer genes display point mutations such as base changes, insertions and deletions that initiate and promote cancer growth and spread. Somatic hypermutation is a powerful mechanism for generation of different mu...

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Autors principals: Kashuba, Vladimir I., Pavlova, Tatiana V., Grigorieva, Elvira V., Kutsenko, Alexey, Yenamandra, Surya Pavan, Li, Jingfeng, Wang, Fuli, Protopopov, Alexei I., Zabarovska, Veronika I., Senchenko, Vera, Haraldson, Klas, Eshchenko, Tatiana, Kobliakova, Julia, Vorontsova, Olga, Kuzmin, Igor, Braga, Eleonora, Blinov, Vladimir M., Kisselev, Lev L., Zeng, Yi-Xin, Ernberg, Ingemar, Lerman, Michael I., Klein, George, Zabarovsky, Eugene R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684631/
https://ncbi.nlm.nih.gov/pubmed/19478941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005231
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