High Mutability of the Tumor Suppressor Genes RASSF1 and RBSP3 (CTDSPL) in Cancer

BACKGROUND: Many different genetic alterations are observed in cancer cells. Individual cancer genes display point mutations such as base changes, insertions and deletions that initiate and promote cancer growth and spread. Somatic hypermutation is a powerful mechanism for generation of different mu...

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Bibliografiska uppgifter
Huvudupphovsmän: Kashuba, Vladimir I., Pavlova, Tatiana V., Grigorieva, Elvira V., Kutsenko, Alexey, Yenamandra, Surya Pavan, Li, Jingfeng, Wang, Fuli, Protopopov, Alexei I., Zabarovska, Veronika I., Senchenko, Vera, Haraldson, Klas, Eshchenko, Tatiana, Kobliakova, Julia, Vorontsova, Olga, Kuzmin, Igor, Braga, Eleonora, Blinov, Vladimir M., Kisselev, Lev L., Zeng, Yi-Xin, Ernberg, Ingemar, Lerman, Michael I., Klein, George, Zabarovsky, Eugene R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684631/
https://ncbi.nlm.nih.gov/pubmed/19478941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005231
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