A high throughput Chromatin ImmunoPrecipitation approach reveals principles of dynamic gene regulation in mammals

Understanding the principles governing mammalian gene regulation has been hampered by the difficulty in measuring in-vivo binding dynamics of large numbers of transcription factors (TF) to DNA. Here, we develop a high-throughput Chromatin ImmunoPrecipitation (HT-ChIP) method to systematically map pr...

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Main Authors: Garber, Manuel, Yosef, Nir, Goren, Alon, Raychowdhury, Raktima, Thielke, Anne, Guttman, Mitchell, Robinson, James, Minie, Brian, Chevrier, Nicolas, Itzhaki, Zohar, Blecher-Gonen, Ronnie, Bornstein, Chamutal, Amann-Zalcenstein, Daniela, Weiner, Assaf, Friedrich, Dennis, Meldrim, James, Ram, Oren, Chang, Christine, Gnirke, Andreas, Fisher, Sheila, Friedman, Nir, Wong, Bang, Bernstein, Bradley E., Nusbaum, Chad, Hacohen, Nir, Regev, Aviv, Amit, Ido
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873101/
https://ncbi.nlm.nih.gov/pubmed/22940246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.030
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