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HLA class I alleles are associated with peptide binding repertoires of different size, affinity and immunogenicity()
Prediction of HLA binding affinity is widely utilized to identify candidate T cell epitopes, and an affinity of 500 nM is routinely used as a threshold for peptide selection. However, the fraction (%) of peptides predicted to bind with affinities of 500 nM varies by allele. For example, of a large c...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872965/ https://ncbi.nlm.nih.gov/pubmed/24190657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302101 |
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