Evaluating the Immunogenicity of Protein Drugs by Applying In Vitro MHC Binding Data and the Immune Epitope Database and Analysis Resource

The immune system has evolved to become highly specialized in recognizing and responding to pathogens and foreign molecules. Specifically, the function of HLA class II is to ensure that a sufficient sample of peptides derived from foreign molecules is presented to T cells. This leads to an important...

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Hlavní autoři: Paul, Sinu, Kolla, Ravi V., Sidney, John, Weiskopf, Daniela, Fleri, Ward, Kim, Yohan, Peters, Bjoern, Sette, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816028/
https://ncbi.nlm.nih.gov/pubmed/24222776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/467852
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