Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

T-cells have to recognize peptides presented on MHC molecules to be activated and elicit their effector functions. Several studies demonstrate that some peptides are more immunogenic than others and therefore more likely to be T-cell epitopes. We set out to determine which properties cause such diff...

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Detalhes bibliográficos
Main Authors: Calis, Jorg J. A., Maybeno, Matt, Greenbaum, Jason A., Weiskopf, Daniela, De Silva, Aruna D., Sette, Alessandro, Keşmir, Can, Peters, Bjoern
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808449/
https://ncbi.nlm.nih.gov/pubmed/24204222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003266
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