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Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining

To maintain the integrity of the organism, embryonic stem cells (ESC) need to maintain their genomic integrity in response to DNA damage. DNA double strand breaks (DSBs) are one of the most lethal forms of DNA damage and can have disastrous consequences if not repaired correctly, leading to cell dea...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fan, Jinshui, Robert, Carine, Jang, Yoon-Young, Liu, Hua, Sharkis, Saul, Baylin, Stephen Bruce, Rassool, Feyruz Virgilia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872739/
https://ncbi.nlm.nih.gov/pubmed/21718709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.05.018
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