Processing of DNA for nonhomologous end-joining by cell-free extract
In mammalian cells, nonhomologous end-joining (NHEJ) repairs DNA double-strand breaks created by ionizing radiation and V(D)J recombination. We have developed a cell-free system capable of processing and joining noncompatible DNA ends. The system had key features of NHEJ in vivo, including dependenc...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15692565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600563 |
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