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Processing of DNA for nonhomologous end-joining by cell-free extract

In mammalian cells, nonhomologous end-joining (NHEJ) repairs DNA double-strand breaks created by ionizing radiation and V(D)J recombination. We have developed a cell-free system capable of processing and joining noncompatible DNA ends. The system had key features of NHEJ in vivo, including dependenc...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Budman, Joe, Chu, Gilbert
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2005
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15692565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600563
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