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Concise Synthesis of the Unnatural Sphingosine and Psychosine Enantiomer
The accumulation of psychosine (galactosyl sphingosine) has been associated with the pathogenesis of Krabbe disease, however, the exact mechanism of its cytotoxicity remains unclear. Herein, we describe the synthesis of the unnatural enantiomer of erythrosphingosine, psychosine, and related derivati...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872080/ https://ncbi.nlm.nih.gov/pubmed/24371429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201000024 |
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