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Concise Synthesis of the Unnatural Sphingosine and Psychosine Enantiomer

The accumulation of psychosine (galactosyl sphingosine) has been associated with the pathogenesis of Krabbe disease, however, the exact mechanism of its cytotoxicity remains unclear. Herein, we describe the synthesis of the unnatural enantiomer of erythrosphingosine, psychosine, and related derivati...

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Bibliografski detalji
Glavni autori: Parameswar, Archana R., Hawkins, Jacqueline A., Mydock, Laurel K., Sands, Mark S., Demchenko, Alexei V.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872080/
https://ncbi.nlm.nih.gov/pubmed/24371429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201000024
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