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Concise Synthesis of Both Enantiomers of Pilocarpine
Furan-2-carboxylic acid was used as a starting material for the synthesis of dehydro-homopilopic acid. Esterification, hydrogenation and enzymatic hydrolysis followed by the reduction of Weinreb amides and a single-step attachment of a 1-methyl-imidazole residue allowed for the concise synthesis of...
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| Publicado en: | Molecules |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8235342/ https://ncbi.nlm.nih.gov/pubmed/34208623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123676 |
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