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Synthesis and Cytotoxicity Evaluation of DOTA-Conjugates of Ursolic Acid

In this study, we report the synthesis of several amine-spacered conjugates of ursolic acid (UA) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Thus, a total of 11 UA-DOTA conjugates were prepared holding various oligo-methylene diamine spacers as well as different substituents...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kahnt, Michael, Hoenke, Sophie, Fischer, Lucie, Al-Harrasi, Ahmed, Csuk, René
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630699/
https://ncbi.nlm.nih.gov/pubmed/31212958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24122254
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