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The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes
Microsatellites - simple tandem repeats present at millions of sites in the human genome - can shorten or lengthen due to a defect in DNA mismatch repair. We present here the first comprehensive genome-wide analysis of the prevalence, mutational spectrum and functional consequences of microsatellite...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871995/ https://ncbi.nlm.nih.gov/pubmed/24209623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.015 |
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