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The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes

Microsatellites - simple tandem repeats present at millions of sites in the human genome - can shorten or lengthen due to a defect in DNA mismatch repair. We present here the first comprehensive genome-wide analysis of the prevalence, mutational spectrum and functional consequences of microsatellite...

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Autors principals: Kim, Tae-Min, Laird, Peter W., Park, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871995/
https://ncbi.nlm.nih.gov/pubmed/24209623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.015
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