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A genome-wide view of microsatellite instability: old stories of cancer mutations revisited with new sequencing technologies

Microsatellites are simple tandem repeats that are present at millions of loci in the human genome. Microsatellite instability (MSI) refers to DNA slippage events on microsatellites that occur frequently in cancer genomes when there is a defect in the DNA mismatch repair system. These somatic mutati...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kim, Tae-Min, Park, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233171/
https://ncbi.nlm.nih.gov/pubmed/25371413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1225
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