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Microsatellite Instability in Colorectal Cancer
Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity. MSI is detected in about 15% of all colorectal cancers; 3% are of these are associated with Lynch syndrome and the other 12% are caused by sporadic, acquired hypermethylation of the promo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037515/ https://ncbi.nlm.nih.gov/pubmed/20420947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.12.064 |
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