Identification of pY654-β-catenin as a critical co-factor in hypoxia-inducible factor-1α signaling and tumor responses to hypoxia

Hypoxia is linked to epithelial mesenchymal transition (EMT) and tumor progression in numerous carcinomas. Responses to hypoxia are thought to operate via hypoxia-inducible factors (HIFs), but the importance of co-factors that regulate HIF signaling within tumors is not well understood. Here we eluc...

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Bibliografiske detaljer
Main Authors: Xi, Ying, Wei, Ying, Sennino, Barbara, Ulsamer, Arnau, Kwan, Irene, Brumwell, Alexis N., Tan, Kevin, Aghi, Manish K., McDonald, Donald M., Jablons, David M., Chapman, Harold A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871884/
https://ncbi.nlm.nih.gov/pubmed/23246962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.530
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