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Axin Pathway Activity Regulates in Vivo pY654-β-catenin Accumulation and Pulmonary Fibrosis

Epithelial to mesenchymal transition (EMT) and pulmonary fibrogenesis require epithelial integrin α3β1-mediated cross-talk between TGFβ1 and Wnt signaling pathways. One hallmark of this cross-talk is pY654-β-catenin accumulation, but whether pY654-β-catenin is a biomarker of fibrogenesis or function...

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Autori principali: Ulsamer, Arnau, Wei, Ying, Kim, Kevin K., Tan, Kevin, Wheeler, Sarah, Xi, Ying, Thies, R. Scott, Chapman, Harold A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281604/
https://ncbi.nlm.nih.gov/pubmed/22203675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322123
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