ROS Detoxification and Proinflammatory Cytokines Are Linked by p38 MAPK Signaling in a Model of Mature Astrocyte Activation

Astrocytes are the most abundant glial cell in the retinal nerve fiber layer (NFL) and optic nerve head (ONH), and perform essential roles in maintaining retinal ganglion cell (RGC) detoxification and homeostasis. Mature astrocytes are relatively quiescent, but rapidly undergo a phenotypic switch in...

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Hlavní autoři: Nahirnyj, Adrian, Livne-Bar, Izhar, Guo, Xiaoxin, Sivak, Jeremy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871647/
https://ncbi.nlm.nih.gov/pubmed/24376630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083049
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