Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: Liu, Liping, Yu, Hongli, Wu, Hao, Yang, Xiaolin, Pan, Yaozong, Chen, Yeqing, Wang, Kuilong, Wang, Wei, Zhang, Wenying, Jin, Yangping, Zhang, Chengchao, Jiang, Ai, Xia, Chunyan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2017
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482117/
https://ncbi.nlm.nih.gov/pubmed/28560398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6617
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