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Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was c...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Liu, Liping, Yu, Hongli, Wu, Hao, Yang, Xiaolin, Pan, Yaozong, Chen, Yeqing, Wang, Kuilong, Wang, Wei, Zhang, Wenying, Jin, Yangping, Zhang, Chengchao, Jiang, Ai, Xia, Chunyan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482117/
https://ncbi.nlm.nih.gov/pubmed/28560398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6617
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