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Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was c...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Liu, Liping, Yu, Hongli, Wu, Hao, Yang, Xiaolin, Pan, Yaozong, Chen, Yeqing, Wang, Kuilong, Wang, Wei, Zhang, Wenying, Jin, Yangping, Zhang, Chengchao, Jiang, Ai, Xia, Chunyan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482117/
https://ncbi.nlm.nih.gov/pubmed/28560398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6617
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