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Manganese-induced potentiation of in vitro proinflammatory cytokine production by activated microglial cells is associated with persistent activation of p38 MAPK

Previous studies that investigated the role of inflammation in the neurotoxicity of manganese (Mn) found that Mn enhanced the production of inflammogen (lipopolysaccharide; LPS)-induced proinflammatory cytokines such as IL-6 and TNF-α. Although we have shown that the enhanced cytokine production occ...

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Détails bibliographiques
Auteurs principaux: Crittenden, P. L., Filipov, N. M.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231510/
https://ncbi.nlm.nih.gov/pubmed/17845838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2007.07.004
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