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Synergistic Mechanisms of DNA Demethylation during Transition to Ground-State Pluripotency

Pluripotent stem cells (PSCs) occupy a spectrum of reversible molecular states ranging from a naive ground-state in 2i, to metastable embryonic stem cells (ESCs) in serum, to lineage-primed epiblast stem cells (EpiSCs). To investigate the role of DNA methylation (5mC) across distinct pluripotent sta...

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Bibliografiska uppgifter
Huvudupphovsmän: Hackett, Jamie A., Dietmann, Sabine, Murakami, Kazuhiro, Down, Thomas A., Leitch, Harry G., Surani, M. Azim
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871394/
https://ncbi.nlm.nih.gov/pubmed/24371807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.11.010
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