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Synergistic Mechanisms of DNA Demethylation during Transition to Ground-State Pluripotency
Pluripotent stem cells (PSCs) occupy a spectrum of reversible molecular states ranging from a naive ground-state in 2i, to metastable embryonic stem cells (ESCs) in serum, to lineage-primed epiblast stem cells (EpiSCs). To investigate the role of DNA methylation (5mC) across distinct pluripotent sta...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871394/ https://ncbi.nlm.nih.gov/pubmed/24371807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.11.010 |
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