CotH3 mediates fungal invasion of host cells during mucormycosis

Angioinvasion is a hallmark of mucormycosis. Previously, we identified endothelial cell glucose-regulated protein 78 (GRP78) as a receptor for Mucorales that mediates host cell invasion. Here we determined that spore coat protein homologs (CotH) of Mucorales act as fungal ligands for GRP78. CotH pro...

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Detalhes bibliográficos
Main Authors: Gebremariam, Teclegiorgis, Liu, Mingfu, Luo, Guanpingsheng, Bruno, Vincent, Phan, Quynh T., Waring, Alan J., Edwards, John E., Filler, Scott G., Yeaman, Michael R., Ibrahim, Ashraf S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871245/
https://ncbi.nlm.nih.gov/pubmed/24355926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71349
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